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Bascom Palmer Eye Institute Neuro-Ophthalmology Research Fellowship
Coordinator:
Fellowship Description: A two-year combined research and clinical fellowship in neuro-ophthalmology is offered to foster the development of clinician-scientists who will transform future medical care in the subspecialty. The lead mentor, Dr. John Guy, holds 3 recently awarded NEI grants including the first funded towards development of a gene therapy program of a disorder caused by mutated mitochondrial DNA, Leber Hereditary Optic Neuropathy. The fellowship program provides training in laboratory and clinical investigations, including clinical trials, molecular biology, optic nerve histopathology at both the light and electron microscopic level and gene based therapies utilizing the adeno-associated virus (AAV) employed successfully in a phase I trial for Leber Congential Amaurosis (LCA). The specific objective is to provide the training and mentorship that will lead the fellow to be successful as faculty members in Schools of Medicine by using a multidisciplinary research program that provide training in innovative and effective approaches to the understanding of and therapy for visual disorders. The program includes didactic instruction appropriate to the area being studied, training in laboratory techniques where this represents relevant approaches for the trainee, patient-oriented research experience with one or more Mentors from a team of internationally known neuron-ophthalmologists within an environment that nurtures skills in human research ethics and methodology, along with practical skills in funding and collaboration and patient care. |
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